UNIVERSIDAD NACIONAL DE QUILMES;CHEMO RESEARCH, S.L.
发明人:
LORENZANO MENNA, PABLO,ALONSO,DANIEL FERNANDO,GÓMEZ, DANIEL EDUARDO,COMÍN, JULIETA
申请号:
DK12774997
公开号:
DK2766342T3
申请日:
2012.10.10
申请国别(地区):
DK
年份:
2016
代理人:
摘要:
Provided herein are phenyl-guanidine derivatives for the inhibition of Rac1 which blocks its interaction with guanosine exchange factors (GEFs) belonging to the DBL family as agents for the treatment of aggressive and/or resistant tumors, as well as pharmaceutical compositions comprising them, their use in therapy and processes for their preparation.