Drug eluting stents,methods of making, using, and verifying long-term stability of the drug eluting stents,and methods for predicting long term stent efficacy and patient safety after implantation of a drug eluting stent are disclosured.In one embodiment,a drug eluting stent may include a stent framework；a drug-containing layer；a drug embedded in the drug-containing layer；and a biocompatible base layer disposed over the stent framework and supporting the drug-containing layer.The drug-containing layer may have an uneven coating thickness.In addition or in alternative,the drug-containing layer may be configured to significantly dissolve/dissipate/disappear between 45 days and 60 days after stent implantation.Stents may reduce,minimize,or eliminate patient risks associated with the implantation of a stent,including,for example,restenosis,thrombosis,and/or MACE.
