Improved medical devices and methods are provided that deliver an adhesive sheet or membrane at or near a target tissue site, the medical devices and methods comprise a cannula defining a longitudinal axis and having a proximal end and a distal end, the proximal end of the cannula having an opening configured to receive a flowable material, the distal end of the cannula connected to an expandable member, the expandable member having an interior configured to receive the flowable material and a surface aligned with and contacting at least a portion of the adhesive membrane, the adhesive membrane configured to attach to a select tissue surface of the target tissue site in an open position.
