President and Fellows of Harvard College;The Brigham and Women s Hospital, Inc.
发明人:
Jinjun Shi,Xi Zhu,Omid C. Farokhzad,Xiaoding Xu,Yanlan Liu,Aude Thiriot,Ulrich Von Andrian
申请号:
US15520796
公开号:
US20170304213A1
申请日:
2015.10.23
申请国别(地区):
US
年份:
2017
代理人:
摘要:
This invention relates to amphiphile-polymer particles comprising obtaining a first solution comprising a water-insoluble polymer, a payload and a first amphiphile in a water-miscible solvent; mixing the first solution with an aqueous second solution to form an aqueous composition comprising a particle comprising a water-insoluble polymeric core comprising the water-insoluble polymer; the payload; and the first amphiphile.