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CONDITIONAL KNOCKOUT MUTANTS OF SORTILIN-LIKE RECEPTOR IN APICOMPLEXAN PARASITES AND USES THEREOF
专利权人:
发明人:
申请号:
EP12727384.5
公开号:
EP2723355A1
申请日:
2012.06.14
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
A nucleic acid construct which comprises a sequence of a 5 non-coding and promoter regions of Sortilin of an eukaryote organism, a selection gene cassette, said gene cassette having its own 5 and 3UTR flanking sequence on both side of its coding sequence, a sequence of a 3 coding region of Sortilin of said eukaryote organism, said sequence being driven by an anhydrotetracycline(ATc)-sensitive transactivator and its use in human and veterinarian medicine.
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