CONDITIONAL KNOCKOUT MUTANTS OF SORTILIN-LIKE RECEPTOR IN APICOMPLEXAN PARASITES AND USES THEREOF

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专利权人:

发明人:

申请号：

EP12727384.5

公开号：

EP2723355A1

申请日:

2012.06.14

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

A nucleic acid construct which comprises a sequence of a 5 non-coding and promoter regions of Sortilin of an eukaryote organism, a selection gene cassette, said gene cassette having its own 5 and 3UTR flanking sequence on both side of its coding sequence, a sequence of a 3 coding region of Sortilin of said eukaryote organism, said sequence being driven by an anhydrotetracycline(ATc)-sensitive transactivator and its use in human and veterinarian medicine.

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