According to the method for trading user-based skin condition information based on a base of the present invention, a method implemented through a system including at least one computer that implements a designated blockchain network or interworking with a blockchain network, the information device provided at the designated base If the skin condition information for each user issued in the form of a paper document or a portable medium is transmitted from a designated medical institution or skin condition measurement institution to the skin condition information for each user in the form of an electronic document or digital content that can be transmitted and received through a communication network, the skin The status information collection unit collects skin condition information for each user in the form of an electronic document or digital content from the information device, and the skin condition information storage unit collects skin condition information for each user and designated user identification information collected in the form of an electronic document or digital content. Stores and manages the user's skin condition information mapped to the specified database, and when the specified buyer registers the skin condition information purchase registration information for the purchase of the skin condition information, the token deposit part is the skin condition among the tokens issued through the designated blockchain network. In order to proceed with the purchase of skin condition information corresponding to the information purchase registration information, a procedure of depositing a token purchased or issued to the purchaser into an electronic wallet for purchasing specified skin condition information is performed, and the skin condition information purchase registration information of the buyer When the at least one user is notified through the web or the app and requests the skin condition information transaction based on the known skin conditi