Krishna Devarakonda,Michael J. Giuliani,Vishal K. Gupta,Ralph A. Heasley,Susan Shelby
申请号：
US14479129
公开号：
US09539328B2
申请日:
2014.09.05
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present disclosure provides an extended release pharmaceutical composition comprising hydrocodone and acetaminophen that provides a rapid onset of analgesia, and reduced levels of acetaminophen near the end of the dosing interval. Also provided are methods for reducing the risk of acetaminophen-induced hepatic damage in a subject being treated with an acetaminophen containing composition, as well as methods for treating pain in a subject in need thereof.
