Krishna Devarakonda,Michael J. Giuliani,Vishal K. Gupta,Ralph A. Heasley,Susan Shelby
申请号：
US13473578
公开号：
US08858963B1
申请日:
2012.05.16
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present disclosure provides an extended release pharmaceutical composition comprising hydrocodone and acetaminophen that provides a rapid onset of analgesia, and reduced levels of acetaminophen near the end of the dosing interval. Also provided are methods for reducing the risk of acetaminophen-induced hepatic damage in a subject being treated with an acetaminophen containing composition, as well as methods for treating pain in a subject in need thereof.
