Hsiu-Kang Chang;Tsang-Hsien Alexander Wu;Win-Ping Deng;Hung-Chien Wei
发明人:
Win-Ping Deng,Hsiu-Kang Chang,Hung-Chien Wei,Tsang-Hsien Alexander Wu
申请号:
US12844044
公开号:
US08771705B2
申请日:
2010.07.27
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A method for inhibiting growth and/or metastasis of a tumor in a mammal is disclosed. The method comprises administering to a mammal in need thereof an effective amount of stem cells comprising a transgene encoding at least one oncogenic protein, wherein the stem cells are immortal and show no signs of neoplastic transformation; and administering to the mammal a vaccine composition comprising an effective amount of at least one immunogenic protein capable of eliciting at least one antibody specific against the at least one oncogenic protein, and thereby inhibiting growth and/or metastasis of a tumor in the mammal. A therapeutic kit for inhibiting growth and/or metastasis of a tumor in a mammal is also disclosed.