PROTHENA BIOSCIENCES LIMITED;UNIVERSITY OF MUNSTER
发明人:
TAM, STEPHEN JED,YEDNOCK, THEODORE,LIU, YUE,SCHWAB, NICHOLAS,WIENDL, HEINZ,SCHNEIDER-HOHENDORF, TILMAN
申请号：
CA2938945
公开号：
CA2938945A1
申请日:
2015.03.12
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The present application provides evidence that a combined blockade against alpha-4 integrin and MCAM is more effective than against either molecule alone. In consequence, the invention provides methods of combination treatment in which both an antagonist of alpha-4 integrin and an MCAM antagonist are administered to a subject having or at risk of multiple sclerosis or other autoimmune disease.
