#$%^&*AU2015201828A120150430.pdf#####ABSTRACT The invention relates to the use of a virus, preferably an adenovirus, for producing a medicament. Said virus is replication-deficient in cells which do not contain YB-I in the core and codes for an oncogene or oncogene product, especially an oncogene protein, which transactivates at least one viral gene, preferably an adenoviral gene, said gene being selected among the group comprising EIB55kDa, E4orf6, E4orf3, and E3ADP.