Inhibitor of the expression of cancer-promoting factors, screening method for active ingredient thereof, expression cassette useful in said method, diagnostic drug, and diagnostic method
Nippon Zoki Pharmaceutical Co., Ltd.;National University Corporation Tokyo Medical and Dental University
发明人:
ASAHARA, Hiroshi,CHIBA, Tomoki,ABE, Kentaro
申请号：
AU2018364001
公开号：
AU2018364001A1
申请日:
2018.11.09
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
The purpose of this invention is to discover a novel factor which affects the level of expression of cancer-promoting factors, to provide an inhibitor of the expression of cancer promoting-factors and development tool therefor, which are based on this novel factor, and to provide a cancer diagnostic drug and a diagnostic method. Provided are: an inhibitor for the expression of cancer-promoting factors, containing at least one inhibitor selected from the group consisting of inhibitors of RBMS expression and inhibitors of RBMS function； a screening method which uses RBMS expression or function as an indicator； an expression cassette useful in said method； a cancer diagnostic drug containing an agent for detecting RBMS gene expression products； and a cancer detection method which takes the level of expression of the RBMS gene as an indicator.
