INHIBITOR OF THE EXPRESSION OF CANCER-PROMOTING FACTORS, SCREENING METHOD FOR ACTIVE INGREDIENT THEREOF, EXPRESSION CASSETTE USEFUL IN SAID METHOD, DIAGNOSTIC DRUG, AND DIAGNOSTIC METHOD
NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY;NIPPON ZOKI PHARMACEUTICAL CO., LTD.
发明人:
ASAHARA, Hiroshi,CHIBA, Tomoki,ABE, Kentaro
申请号:
SG11202004097R
公开号:
SG11202004097RA
申请日:
2018.11.09
申请国别(地区):
SG
年份:
2020
代理人:
摘要:
The purpose of this invention is to discover a novel factor which affects the level of expression of cancer-promoting factors, to provide an inhibitor of the expression of cancer promoting-factors and development tool therefor, which are based on this novel factor, and to provide a cancer diagnostic drug and a diagnostic method. Provided are: an inhibitor for the expression of cancer-promoting factors, containing at least one inhibitor selected from the group consisting of inhibitors of RBMS expression and inhibitors of RBMS function; a screening method which uses RBMS expression or function as an indicator; an expression cassette useful in said method; a cancer diagnostic drug containing an agent for detecting RBMS gene expression products; and a cancer detection method which takes the level of expression of the RBMS gene as an indicator.