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ENZYMATICALLY HYDROLYSED PECTIC POLYSACCHARIDES FOR TREATING OR PREVENTING INFECTIONS
专利权人:
NutriLeads B.V.
发明人:
Ruud ALBERS,Maria TZOUMAKI
申请号:
US16855568
公开号:
US20200246373A1
申请日:
2020.04.22
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention relates to a product for use in the therapeutic or prophylactic treatment of infections, said treatment comprising oral administration of the product, wherein the product is selected from a nutritional formulation, a food product, a dietary supplement, a beverage and a pharmaceutical product, said product containing carrot RG-I polysaccharides having the following combination features:a molecular weight in the range 10-300 kDa;a backbone consisting of galacturonic acid residues and rhamnose residues, said rhamnose residues being contained in alpha(1→;4)-galacturonic-alpha(1→;2)-rhamnose residues;the following monosaccharide composition: 20-60 mol. % galacturonic acid residues, wherein the individual galacturonic acids can be methylated and/or acetyl-esterified;8-50 mol. % rhamnose residues;0-40 mol. % arabinose residues;0-40 mol. % galactose residues;molar ratio of galacturonic acid residues to rhamnose residues in the range of 5:1 to 1:1;galacturonic acid residues, rhamnose residues, arabinose residues and galactose residues together constitute at least 85 mol. % of the monosaccharide residues in the carrot RG-I polysaccharides.These carrot RG-I polysaccharides can be produced by partially hydrolysing pectic polysaccharides present in a carrot pectin isolate. The effectiveness of carrot RG-I polysaccharides against infections is substantially improved by enzymatically hydrolysing the RG-I polysaccharides to remove at least part of the homogalacturonan component.
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