Jin Ryul Son;Sung Wan Lee;Min Gyu Song;Won Hwa Ko;Ja Hyun Cha;Jae Uk Cha;Eun Hee Park;Hyon Ho Baek
发明人:
Jin Ryul Son,Hyon Ho Baek,Eun Hee Park,Sung Wan Lee,Min Gyu Song,Ja Hyun Cha,Jae Uk Cha,Won Hwa Ko
申请号：
US13634590
公开号：
US08710105B2
申请日:
2011.02.21
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A method of preparing enteric hard capsules, and an enteric hard capsule prepared by the method. The method may include: dissolving an enteric base material, a capsule forming aid, and a neutralizing agent in water at room temperature to prepare an aqueous composition； heating the aqueous composition to a first temperature that is higher than a gelation start temperature of the aqueous composition； cooling the heated aqueous composition to a second temperature that is lower than the gelation start temperature； immersing a mold pin heated to a third temperature that is higher than the gelation start temperature into the aqueous composition； removing the mold pin from the aqueous composition to obtain a film coated on the mold pin； maintaining the film on the mold pin at a fourth temperature that is higher than the gelation start temperature for a first time period to fix the film onto the mold pin； and drying the fixed film at a fifth temperature for a second time period to obtain a capsule shell.
