Cynthia Bamdad,Benoit Smagghe,Mark Carter,Andrew Stewart
申请号：
US15740654
公开号：
US20180235193A1
申请日:
2016.07.01
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present application discloses a method for generating human tissues in a non-human animal comprising: (i) generating human naïve state stem cells and injecting them into a blastocyst or embryo of a non-human animal such that a chimeric animal is generated； (ii) harvesting human tissues, organs, cells or factors secreted by or made in the human tissues or cells from the chimeric animal； and (iii) transplanting or administering the harvested material into a human resulting in generation of human tissues in a non-human animal.
