עכברים בעלי שינויי mhc גנטיים

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专利权人:

REGENERON PHARMACEUTICALS INC.

发明人:

申请号：

IL25202217

公开号：

IL252022D0

申请日:

2017.04.30

申请国别(地区):

IL

年份:

2017

代理人:

摘要：

The invention provides genetically modified non-human animals that express chimeric human/non-human MHC I polypeptide and/or human or humanized beta2 microglobulin polypeptide, as well as non-human embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified animals and methods of making the same. Methods of using the genetically modified animals to study various aspects of human immune system are provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/