Transgenic mice expressing chimeric major histocompatibility comples (MHC) class II molecules

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专利权人:

Inc.;Regeneron Pharmaceuticals

发明人:

Macdonald, Lynn,Murphy, Andrew J.,Tu, Naxin,Gurer, Cagan,Voronina, Vera,Stevens, Sean

申请号：

AU2014249148

公开号：

AU2014249148A1

申请日:

2014.03.11

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

[00147] The invention provides genetically modified non-human animals that express a humanized MHC II protein (humanized MHC II and polypeptides), as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified animals and methods of making the same. Methods of using the genetically modified animals to study various aspects of human immune system are provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/