Shuichi Mizuno,Akihiko Kusanagi,Laurence J. B. Tarrant,Toshimasa Tokuno,Robert Lane Smith
申请号:
US11413419
公开号:
US08906686B2
申请日:
2006.04.28
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Neo-cartilage constructs suitable for implantation into a joint cartilage lesion in situ and a method for repair and restoration of function of injured, traumatized, aged or diseased cartilage. The construct comprises at least chondrocytes incorporated into a support matrix processed according to the algorithm comprising variable hydrostatic or atmospheric pressure or non-pressure conditions, variable rate of perfusion, variable medium composition, variable temperature, variable cell density and variable time to which the chondrocytes are subjected.