Shuichi Mizuno,Akihiko Kusanagi,Laurence J.B. Tarrant,Toshimasa Tokuno,R. Lane Smith
申请号:
US15185898
公开号:
US20160367727A1
申请日:
2016.06.17
申请国别(地区):
US
年份:
2016
代理人:
摘要:
One-cartilage constructs suitable for implantation into a joint cartilage lesion in sit-up and a method for repair and restoration of function of injured, traumatic, aged or diseased cartilage. The construct comprises at least chondrocytes incorporated into a support matrix processed according to the algorithm comprising variable hydrostatic or atmospheric pressure or non-pressure conditions, variable rate of perfusion, variable medium composition, variable temperature, variable cell density and variable time to which the chondrocytes are subjected.