PURPOSE: A novel C-aryl glucoside is provided to treat and prevent type 2 diabetes, insulin resistant disease, and obesity.CONSTITUTION: A novel C-aryl glucoside is denoted by chemical formula 1. The compound of chemical formula 1 is 2-&lsqb4-chloro-2-&lsqb1,3&rsqbdioxolan-2-yl-5-(4-ethylbenzyl)phenyl&rsqb-6-hydroxymethyl-tetrahydropyrane-3,4,5-triol or 2-&lsqb4-chloro-2-&lsqb1,3&rsqbdioxolan-2-yl-5-(4-ethoxybenzyl)phenyl&rsqb-6-hydroxymethyl-tetrahydropyrane-3,4,5-triol. A pharmaceutical composition for preventing and treating diabetes, insulin resistant diseases, or obesity contains the compound of chemical formula 1 or pharmaceutically acceptable salt thereof as an active ingredient.COPYRIGHT KIPO 2012본 발명은 나트륨 의존 글루코즈 운반체 저해제로서 신규한 C-아릴 글루코사이드 및 그의 제조방법에 관한 것으로, 본 발명에 따른 C-아릴 글루코사이드는 신장에서 일어나는 나트륨 의존 글루코즈 운반체 저해제로서 작용하여, 당뇨병 특히 2형 당뇨병 뿐만 아니라 인슐린 저항성 질환 및 비만을 포함하는 질환의 치료 및 예방에 유용하다.
