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ORALLY DISINTEGRATING TABLET OF NABILONE COMPRISING MANNITOL-BASED GRANULES
专利权人:
Pharmascience Inc.
发明人:
DIALLO, Ousmane,PHILIP, Mathew,TALWAR, Naresh
申请号:
EP15759040
公开号:
EP3113770A4
申请日:
2015.03.04
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
Orally disintegrating medicaments comprising Nabilone allow for improved treatment of nausea arising from chemo therapy for cancer. The medicaments comprise appropriate excipients such that the medicament disintegrates in the mouth in 30 seconds or less, while exhibiting sufficient stability for storage. In a preferred embodiment, the medicament is in the form of a tablet formed from granules. The granules consist of an intra-granular fraction comprising nabilone, mannitol, and polyvinyl pyrrolidone and an extra-granular fraction comprising mannitol, calcium silicate, crospovidone, and magnesium stearate. Processes for manufacturfing such medicaments are also disclosed.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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