(6S,9aS)-N-benzyl-6-[(4-hydroxyphenyl)methyl]-4,7-dioxo-8-({6-[3-(piperazin-1-yl)azetidin-1-yl]pyridin-2-yl}methyl)-2-(prop-2-en-1-yl)-octahydro-1H-pyrazino[2,1-c][1,2,4]triazine-1-carboxamide compound

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专利权人:

Eisai R&D Management Co., Ltd.;PRISM Pharma Co., Ltd.

发明人:

Satoshi Inoue,Yuji Yamamoto,Kentaro Iso

申请号：

US14577660

公开号：

US09174998B2

申请日:

2014.12.19

申请国别(地区):

US

年份:

2015

代理人:

摘要：

A compound represented by formula (1) or pharmaceutically acceptable salt thereof:wherein R1 is a C1-6 alkyl group； R2 and R3 are the same or different from each other and each is a hydrogen atom or a C1-6 alkyl group； X2, X3 and X4 are the same or different from each other and each is a hydrogen atom or a halogen atom； and X5 is a hydrogen atom or —P(═O)(OH)2 has a Wnt Pathway modulating activity.

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