However, methods for introducing a molecule into the cytosol of a cell, for killing a cell, for expressing an antigenic molecule or a portion thereof on the surface of a cell, and for treating or preventing a disease, disorder or infection in a patient, pharmaceutical composition, cell or cell population, and kit
ANDERS HØGSET,KRISTIAN BERG,MÁR MÁSSON,VIVEK S. GAWARE
申请号：
BR112014028315
公开号：
BR112014028315A2
申请日:
2013.05.14
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
The present invention relates to novel chitosan-based conjugates, e.g. nanocarriers, comprising a derivative of the biocompatible polymer chitosan conjugated to a photosensitizing agent, and uses thereof in photochemical internalization (PCI) and photodynamic therapy (PDT). The invention also relates to the use of the novel conjugates of the invention in treatment or prevention of diseases, particularly cancer, and for vaccination purposes.
