PEARSON, RYAN,GETTS, DANIEL R.,PUISIS, JOHN,HERRMANN, JAMES
申请号:
CA3008892
公开号:
CA3008892A1
申请日:
2016.12.22
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention provides compositions comprising tolerizing immune modified particles (TIMPs) and methods for using and making said TIMPs. In particular, carrier polymer is covalently conjugated with antigenic peptide before particle formation, which allows for exquisite control of particle size and antigen encapsulation (e.g., for use in eliciting induction of immunological tolerance).