A high-frequency induction atomization device for delivers an atomized physiological active substance for absorption through the respiratory tract. The device includes a housing and an atomizing core (1), a high-frequency generator (6), a sensor (7) and a power supply unit (10) provided in the housing. The power supply unit (10), the sensor (7) and the high-frequency generator (6) are installed in the housing sequentially. The atomizing core (1) is inserted into the high frequency coil (3). A gap functioning as a gas flow channel is left between the atomizing core (1) and the high frequency coil (3). The electric current of the atomizing core (1) is produced by high-frequency induction. The atomizing core (1) is removable, low in cost, and easy in batch process.