A high-frequency induction atomization device for delivering physiological active substance in atomizing form into a lung for absorption through a respiratory tract includes a housing and an atomizing core (1), a high-frequency generator (6), a sensor (7) and a power supply unit (10) provided in the housing. The power supply unit (10), the sensor (7) and the high-frequency generator (6) are installed in the housing sequentially. The sensor (7) and the high-frequency generator (6) are electrically connected with the power supply unit (10) respectively. The high-frequency generator (6) is provided with an air hole (5), the high-frequency generator (6) is provided with a high frequency coil (3), the atomizing core (1) installed in the housing is inserted into the high frequency coil (3), a gap functioned as a gas flow channel is left between the atomizing core (1) and the high frequency coil (3). The inspiratory end of the housing is provided with an air entry (16), and the housing is provided with an inflow port (9). The exothermic electric current of the atomizing core (1), which is stable in performance, is produced by the high-frequency induction. The atomizing core (1) is removable, low in cost, and easy in batch process. The quantitative atomizing is realized by replacing atomizing core (1).