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NEW NON-PEPTIDE DERIVATIVES AS BRADYKININ B1 ANTAGONISTS
专利权人:
RICHTER GEDEON NYRT.
发明人:
VAGO, ISTVAN,FARKAS, SANDOR,HORNOK, KATALIN,BEKE, GYULA,BOZO, EVA,VASTAG, MONIKA,SZENTIRMAY, EVA,KESERU, GYORGY,SCHMIDT, EVA
申请号:
NZ58491207
公开号:
NZ584912A
申请日:
2007.10.27
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
The disclosure relates to bradykinin B1 receptor antagonist phenylsulfamoyl benzamide derivatives of formula (I), wherein R1 - R5, Q and Z are as defined in the specification, and optical antipodes or racemates and/or salts and/or hydrates and/or solvates thereof, which are selective antagonists of bradykinin B1, to processes for producing these compounds, to pharmacological compositions containing them and to their use in therapy or prevention of painful and inflammatory conditions.
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