Ian M. Bell,Steven N. Gallicchio,Craig A. Stump,Cory R. Theberge,Joseph P. Vacca,C. Blair Zartman,Xufang Zhang
申请号：
US12718386
公开号：
US08133891B2
申请日:
2010.03.05
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention is directed to compounds of Formula I: I (where A1, A2, B1, B2, B3, B4, D1, D2, J, K, T, U, V, W, X, Y, Z, R4, R5a, R5b, R5c, m and n are defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
