Композиция на основе интерферона I или III типа и гамма-D-глутаминил-L-триптофана для профилактики и лечения инфекционных заболеваний и иммунодефицитных состояний (варианты)
Общество с ограниченной ответственностью "РД-Биотех" (ООО "РД-Биотех") (RU)
发明人:
Безрукова Евгения Валерьевна (RU),Духовлинов Илья Владимирович (RU),Ищенко Александр Митрофанович (RU),Кадыков Александр Леонидович (RU),Колобов Александр Александрович (RU),Петров Александр Владимиро
申请号：
RU2014144243
公开号：
RU2014144243A
申请日:
2014.10.31
申请国别(地区):
RU
年份:
2016
代理人:
摘要：
1. Composition based on interferon type I or III and gamma-D-glutaminyl-L-tryptophan in an effective amount for the prevention and treatment of infectious diseases, and immunodeficiency sostoyaniy.2. The liquid dosage form composition according to claim 1, characterized in that the additive further comprises a target, the following ratio:... I interferon or type III 10 thousand ME - 25 million MEgamma-D-glutaminyl-L-tryptophan, 0.01-10 0 mgpoliglyukin 0.5 (0,05-20,0) mg / mlEDTA 0.001 (0.0001-0.1) Mtvin-20 0.01 (0,01-5,5)% ves.natriya phosphate dibasic anhydrous 1,8 (0,9-8,0) mg / mlnatriya phosphate monobasic monohydrate 1.3 (0,7-6,5) mg / mlnatry chloride 7.5 (0.5-7.5) mg / ml. 3. The liquid dosage form according to claim. 2, characterized in that it is used for inektsiy.4. The liquid dosage form according to claim. 2, characterized in that it is applied in the form kapel.5. The liquid dosage form according to claim. 2, characterized in that it comprises an interferon type I or III in an amount of from 10 thousand. ME to 10 million ME, further comprising alfa-tocopherol in an amount of 1 × 10 (1 × 10-1 × 10) M , benzalkonium chloride in an amount of 0.005 (0.001-0.04%) and nitrogen, for use as a liquid aerosol or spreya.6. The lyophilized dosage form composition according to claim 1, characterized in that it is used as powder for inhalation, in the following ratio:... I interferon or type III 10 thousand ME - 10 million MEgamma-D-glutaminyl-L-tryptophan 0.01 -10.0 mg.7. The lyophilized dosage form composition according to claim 1, characterized in that it further comprises a target additive in the following ratio (wt.%): Interferon I or III type 10 thousand ME - 10 million MEgamma-D-glutaminyl-L-tryptophan... 0.01-10.0 mgsaharoza 8 (0,5-20,0) gelatin 2% (0.2-10.0) 1% soybean flour (0.1-10.0) polyglukin 1% (0.1 -10.0) 0.5% ascorbic acid (0.05-5) 1% cocoa powder (0.1-10)%. 8. The lyophilized dosage form according to claim. 7, characterized in that it is applied in t
