The present invention relates to a novel piperine derivative and a method of producing the derivative. In addition, the present invention relates to a pharmaceutical composition comprising the piperine derivative for preventing or treating metabolic diseases including obesity, diabetes, dyslipidemia, and fatty liver. The novel piperine derivative according to the present invention is represented by chemical formula 1 and is useful in the treatment of metabolic diseases including obesity, diabetes, dyslipidemia, and fatty liver.COPYRIGHT KIPO 2018본 발명은 신규한 피페린 유도체 및 이들 유도체의 제조방법에 관한 것이다.또한, 본 발명은 상기 피페린 유도체를 포함하는 비만, 당뇨, 이상지질혈증 및 지방간을 포함하는 대사성질환의 예방 또는 치료용 약학적 조성물에 관한 것이다.