Embodiments disclosed herein relate to methods, devices, and computer systems thereof for visibly or non-visibly indicating a subject has received a medical treatment. In certain embodiments, a subject receives an information mark in conjunction with a medical treatment. In certain embodiments, the information mark includes unique information relating to the subject. In certain embodiments, the information mark is fluorescent or phosphorescent. In certain embodiments, the information mark includes one or more magnetic particles. In certain embodiments, the information mark includes a combination of magnetic particles, fluorescent particles, phosphorescent particles, and/or multi-spectral ink. In certain embodiments, devices, computer systems, and methods relate to reading an information mark on a subject, and optionally determining if further medical treatment of the subject is warranted. In certain embodiments, receipt of an information mark entitles a subject to a reward.