MENDLEIN, JOHN, D.,FAROUZ, FRANCINE, S.,THIES, R., SCOTT,SHOEMAKER, DANIEL
申请号：
EP10754130
公开号：
EP2408444A4
申请日:
2010.03.18
申请国别(地区):
EP
年份:
2012
代理人:
摘要：
Provided are improved pharmaceutical compositions that comprise ligands or agonists to prostaglandin EP receptors, and/or cyclic AMP enhancers, and suitable organic solvents that are substantially free of methyl acetate, the compositions being provided for storage and/or use in an endotoxin-free vessel, such as a tube or PE bag. The compositions are suitable for in vitro, ex vivo, and in vivo use, and in particular for ex vivo therapeutic use, such as in hematopoietic stem cell transplants. Also provided are methods of using the compositions in ex vivo therapeutic applications, and methods of preparing the compositions. Kits with instructions on use are also provided.
