HUMAN USE OF GENMANIPULATED ANTIGENRECEPTOR (CAR) T-cells

• 收藏
• 分享

专利权人:

Board of Regents; The University of Texas System

发明人:

COOPER, Laurence, J.N.,WANG-JOHANNING, Feng,TORIKAI, Horoki,HULS, Helen,HURTON, Lenka,OLIVARES, Simon,ZHANG, Ling,KRISHNAMURTHY, Janani

申请号：

DK14798046

公开号：

DK2997134T3

申请日:

2014.05.14

申请国别(地区):

DK

年份:

2020

代理人:

摘要：

The present invention concerns methods and compositions for immunotherapy employing a modified T cell comprising a chimeric antigen receptor (CAR). In particular aspects, CAR-expressing T-cells are producing using electroporation in conjunction with a transposon-based integration system to produce a population of CAR-expressing cells that require minimal ex vivo expansion or that can be directly administered to patients for disease (e.g., cancer) treatment.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/