PULE, MARTIN,CORDOBA, SHAUN,ONUOHA, SHIMOBI,THOMAS, SIMON
申请号:
CA2970440
公开号:
CA2970440A1
申请日:
2015.12.23
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention provides a cell which co-expresses a first chimeric antigen receptor (CAR) and second CAR at the cell surface, each CAR comprising an antigen-binding domain, wherein the antigen-binding domain of the first CAR binds to CD19 and the antigen- binding domain of the second CAR binds to CD22.