A method for treating immunological diseases and/or disorders associated with tumor necrosis factor-alpha (TNF-α) are disclosed. The method comprises administering to a subject in need thereof a therapeutically effective amount of the coconut water extract or the coconut shell extract through induction of transforming growth factor beta (TGF-β) or interleukin-10 (IL-10) as an endogenous immunosuppressive factor.本發明揭露一種用於治療與腫瘤壞死因子α(tumor necrosis factor-alpha,TNF-α)相關聯之免疫疾病及/或異常之方法。該方法包含對其需要的對象投予治療有效量的椰子水萃取物或椰子殼萃取物,以誘導轉化生長因子β(transforming growth factor-β,TGF-β)或白細胞介素10(interleukin-10,IL-10)作為內生性免疫抑制因子。