MULLER, GEORGE W,STIRLING, DAVID,CHEN, ROGER, SHEN-CHU
申请号：
HK10109800.9
公开号：
HK1143360B
申请日:
1999.12.24
申请国别(地区):
HK
年份:
2012
代理人:
摘要：
Substituted 2-(2,6-dioxopiperidin-3-yl)phtalimides and l-oxo-2-(2,6-dioxopiperidin-3-yl)isoindolines reduce the levels of TNF alpha in a mammal. Typical embodiments are 1-oxo-2(2,6-dioxo-3-methylpiperidin-3-yl)-4,5,6,7-tetrafluoroisoindoline and 1,3-dioxo-2-(2,6-dioxo-3-methylpiperidin-3-yl)-4-aminoisoindoline.
