MULLER, George W.,STIRLING, David I.,CHEN, Roger Shen-Chu
申请号：
ES97936295
公开号：
ES2187805T7
申请日:
1997.07.24
申请国别(地区):
ES
年份:
2018
代理人:
摘要：
Substituted 2-(2,6-dioxopiperidin-3-yl)phtalimides and l-oxo-2-(2,6-dioxopiperidin-3-yl)isoindolines reduce the levels of TNF alpha in a mammal. Typical embodiments are 1-oxo-2(2,6-dioxo-3-methylpiperidin-3-yl)-4,5,6,7-tetrafluoroisoindoline and 1,3-dioxo-2-(2,6-dioxo-3-methylpiperidin-3-yl)-4-aminoisoindoline.
