Yissum Research Development Company of the Hebrew University of Jerusalem LTD
发明人:
Yinon Ben Neriah,Guy Brachya,Ido Burstain,Waleed Minzel,Irit Snir-Alkalay,Joseph Vacca,Dansu Li
申请号：
US15748536
公开号：
US10376511B2
申请日:
2016.08.04
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention provides pyrazole pyrimidine derivatives which inhibit Casein kinase I (CKI) and/or Interleukin-1 receptor-associated kinase 1 (IRAKI) and methods of their manufacture, compositions comprising them and uses thereof in methods of treating malignant disease and disorders and methods for treating inflammatory diseases and disorders.
