PROBLEM TO BE SOLVED: To provide a method for producing a collagen repair/detoxification accelerator having the performance of inducing the expression of Hsp90, gp96, Hsp70, gp47 effective for restoring collagen and promoting detoxification.SOLUTION: The method for producing the collagen repair/detoxification accelerator comprises: a step of co-cultivating two or more kinds of lactic acid bacteria to produce a lactic acid bacterial product a step of mixing a metabolic product of bacteria including ethanol, natural alkaline hot spring water, and lactic acid bacteria, in a predetermined ratio with respect to the lactic acid bacterial product a step of aging an aqueous solution obtained by mixing for a predetermined period of time and a step of filtering the precipitate in the aqueous solution obtained by aging.SELECTED DRAWING: NoneCOPYRIGHT: (C)2017,JPO&INPIT【課題】コラーゲンの修復や排毒促進に有効なHsp90、gp96、Hsp70、gp47の発現誘導性能を有するコラーゲン修復・排毒促進剤の製造方法を提供する。【解決手段】コラーゲン修復・排毒促進剤の製造方法は、複数種の乳酸菌を共生培養して乳酸菌生産物質を生成する工程と、乳酸菌生産物質に対して所定の割合でエタノール、天然アルカリ温泉水、及び乳酸菌を含む菌の代謝産物を混合する工程と、混合して得られた水溶液を所定の期間熟成する工程と、熟成して得られた水溶液中の沈殿物を濾過する工程と、を含む。【選択図】なし
