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Method for the preparation of oral capsule and the oral composition containing the capsule powder prepared by the same
专利权人:
发明人:
김대경,강계홍,김기정,이병렬
申请号:
KR1020060092357
公开号:
KR1012727380000B1
申请日:
2006.09.22
申请国别(地区):
KR
年份:
2013
代理人:
摘要:
A method for preparing an oral granule is provided to obtain the oral composition which is added to an oral composition, thereby improving the stability of oral effective ingredients, being safe to oral mucosa and showing excellent periodental disease preventing, dental caries preventing and bad smell inhibiting effects. A method for preparing an oral granule comprises the steps of: (a) dissolving an oral effective ingredient in an aqueous binder solution where at least one selected from the group consisting of microcrystalline cellulose, white sugar and starch is dispersed to prepare a layering binder solution; and (b) coating an inert core with the layering binder solution using a fluid bed coater to prepare a spherical granule. The method further comprises a step of coating a layering binder solution including TiO2 or ZnO on the granule after the step(b). An oral composition comprises 0.05-5 wt.% of the prepared oral granule regarding the total weight of the composition. Further, the fluid bed coater uses a tangential spray system.본 발명은 구강용 과립의 제조방법 및 이 방법에 의해 제조된 과립을 함유하는 구강용 조성물에 관한 것으로, 더욱 상세하게는 구강질환의 예방 및 치료효과가 있는 식물 추출물 및 화합물을 유동층 코팅기(fluid bed coater)를 사용하여 구형태의 구강용 과립을 제조하고 이를 구강용 조성물에 첨가함으로써 구강질환의 예방 및 치료효과가 뛰어나고, 사용시 자극이 적고 안전하며, 구강용 유효성분의 안정성이 향상된 구강용 조성물에 관한 것이다.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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