The present disclosure generally relates to pediatric nutritional compositions including a prebiotic mixture of galacto-oligosaccharide and/or polydextrose, a probiotic, such as Lactobacillus rhamnosus GG, and human milk oligosaccharides. More particularly, the present disclosure relates to a nutritional composition having: (i) a protein source, (ii) a lipid source, (iii) a carbohydrate source, (iv) a human milk oligosaccharide or a precursor thereof, (v) polydextrose and/or galacto-oligosaccharides, and (vi) a probiotic. The disclosed nutritional compositions advantageously promote the gut-brain axis.本揭示內容大致關於包括半乳-寡醣(galacto-oligosaccharide)和/或聚右旋糖(polydextrose)、益生菌(諸如鼠李糖乳酸桿菌(Lactobacillus rhamnosus GG))、和人乳寡醣之益生質混合物的兒童營養組成物。更具體而言,本揭示內容關於一種營養組成物,其具有(i)蛋白質來源、(ii)脂質來源、(iii)碳水化合物來源、(iv)人乳寡醣或其前驅物、(v)聚右旋糖和/或半乳-寡醣、及(vi)益生菌。所揭示之營養組成物有利地促進腸腦軸(gut-brain axis)。