The present invention relates to manufacturing processes for the preparation of a pharmaceutical dosage form comprising nifedipine and candesartan cilexetil and optionally at least one diuretic characterized in that nifedipine is released in the body in a controlled (modified) manner and the candesartan cilexetil is released rapidly (immediate release (IR)) and optionally the diuretic is released rapidly (immediate release (IR)) and the pharmaceutical dosage forms obtainable by these processes.本發明係關於用於製備包含尼菲迪平及坎地沙坦西來替昔酯及任意至少一種利尿劑之醫藥劑型的製造方法，其特徵在於尼菲迪平係以一控制(改良)方式於體內釋出且坎地沙坦西來替昔酯係快速釋出(立即釋出(IR))且任意的利尿劑係快速釋出(立即釋出(IR))，以及可藉由這些方法得到之醫藥劑型。
