Adrian Funke,Günter Meyer,Martina Smikalla,Andreas Meeners,Markus Wirges,Daniela Brock,Sarah Just,Peter Kleinebudde,Klaus Knop,Jochen Axel Zeitler,Rolf-Anton Boeggering
申请号:
US13889100
公开号:
US09539176B2
申请日:
2013.05.07
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to manufacturing processes for the preparation of a pharmaceutical dosage form comprising nifedipine and candesartan cilexetil and optionally at least one diuretic characterized in that nifedipine is released in the body in a controlled (modified) manner and the candesartan cilexetil is released rapidly (immediate release (IR)) and optionally the diuretic is released rapidly (immediate release (IR)) and the pharmaceutical dosage forms obtainable by these processes.