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Quetiapine salts and their polymorphs
专利权人:
Girish Dixit
发明人:
Girish Dixit,Anil Shahaji Khile,Jayesh Laljibhai Patel,Nitin Sharadchandra Pradhan,Jon Valgeirsson
申请号:
US12599085
公开号:
US08101597B2
申请日:
2008.05.07
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to novel and stable salt forms of quetiapine, processes for preparation, pharmaceutical compositions, and method of treating thereof. More particularly, the present invention provides novel acid addition salts of quetiapine wherein the acid counter ion is provided by an acid selected from the group consisting of benzene sulfonic acid, dibenzoyl-L-(+)-tartaric acid and di-p-toluoyl-L-(+)-tartaric acid. The present invention also provides novel polymorphic forms of quetiapine salts selected from the group consisting of quetiapine hydrobromide, quetiapine sulfate, quetiapine nitrate and quetiapine citrate.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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