The United States of America; as represented by the Secretary; Department of Health and Human Serv
发明人:
Xiaoyuan Chen,Jibin Song
申请号：
US15781940
公开号：
US20180271788A1
申请日:
2016.12.09
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Disclosed is a method of producing a vesicle containing a metallic nanoparticle that is covalently bound to at least one hydrophilic polymer and at least one hydrophobic polymer, wherein the method involves dispersing the polymer-bound metallic nanoparticle in an organic solvent, adding an aqueous solution containing a dispersing aid to form a mixed solution, sonicating the mixed solution to form an emulsion； and removing the organic solvent from the emulsion until the vesicle forms. Using this method, the formed vesicle has a diameter of 20-150 nm, which is useful for a method of conducting photothermal therapy (PTT) for killing cells, such as cancer cells.
