TCHESSALOV, SERGUEI,KANTOR, ANGELA,LI, LI,LUKSHA, NICHOLAS,WARNE, NICHOLAS
申请号：
EP10790288
公开号：
EP2442798A4
申请日:
2010.06.18
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
The present invention provides, among other things, stable formulations for small modular immunopharmaceutical (SMIP&trade；) proteins. In some embodiments, the present invention provides a formulation containing a lyophilized mixture of a small modular immunopharmaceutical protein, wherein less than 7% of the lyophilized small modular immunopharmaceutical protein exists in aggregated form. Formulations according to the invention may contain buffering agents, stabilizers, bulking agents, surfactants and/or other excipients. The present invention also provides formulations for lyophilization, reconstitution and methods of use thereof.
