Tchessalov, Serguei,Kantor, Angela,Li, Li,Luksha, Nicholas,Warne, Nicholas
申请号：
AU2010263058
公开号：
AU2010263058A1
申请日:
2010.06.18
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The present invention provides, among other things, stable formulations for small modular immunopharmaceutical (SMIP) proteins. In some embodiments, the present invention provides a formulation containing a lyophilized mixture of a small modular immunopharmaceutical protein, wherein less than 7% of the lyophilized small modular immunopharmaceutical protein exists in aggregated form. Formulations according to the invention may contain buffering agents, stabilizers, bulking agents, surfactants and/or other excipients. The present invention also provides formulations for lyophilization, reconstitution and methods of use thereof.
