培美曲塞靜脈注射劑型农业专利-农业专业知识服务系统

发明人:: KUMAR, SAMARTH,库马尔　萨曼撒,庫馬爾　薩曼撒,VARU, RAMAJI KARSHANBHAI,凡路　拉马吉　卡尔桑巴,凡路　拉馬吉　卡爾桑巴,PATEL, NISHIT,巴特尔　尼什特,巴特爾　尼什特,KANE, PRASHANT,凯恩　普拉尚特,凱恩　普拉尚特,BHOWMICK, SUBHAS BALARAM,帕米克　苏巴斯巴拉兰,帕米克　蘇巴斯巴拉蘭

摘要：: The present invention relates to an intravenous infusion dosage form comprising: an aqueous solution of pemetrexed or its pharmaceutically acceptable salt at a concentration ranging from 1.0 mg/ml to 20.0 mg/ml present in a multilayered flexible plastic infusion container, wherein the multilayered flexible plastic infusion container has an oxygen scavenger layer sandwiched between an outermost and an innermost layer of the container, the container being free of a polyamide and wherein the multilayered flexible plastic infusion container filled with the aqueous solution of pemetrexed is autoclavable.本發明涉及一種靜脈注射劑型，包括：以範圍從1.0 mg/ml到20.0 mg/ml的一濃度存在於多層可撓性塑膠注射容器中的培美曲塞或其藥學上可接受的鹽的水溶液，其中該多層可撓性塑膠注射容器具有夾在容器的最外和最內層之間的去氧劑層，該容器不含聚醯胺，並且其中被培美曲塞的水溶液填充的多層可撓性塑膠注射容器是可高壓滅菌的。