The present invention discloses eight novel diterpenoids, i.e. Dysongensins A to H, extracted from the leaves and twigs of Dysoxylum hongkongense, wherein AMBROX® which is applicable in perfume industry is prepared from Dysongensin A via a series of chemical reactions, and cytotoxicity of Dysongensins A to H against human cancer cell lines and their antiviral and anti-inflammatory activities are determined. Therefore, in the present invention, AMBROX® prepared from Dysongensin A affords a new idea for applying as an odorous compound in perfume industry, and the novel diterpenoids can be prepared as a pharmaceutical composition and/or a drug having antiviral, anti-inflammatory and/or anti-cancer activity.本發明揭示由紅果椌木(Dysoxylum hongkongense)枝葉萃取出的八種二萜類化合物,即Dysongenesins A至H,以一連串化學反應由Dysongensin A製備出可應用於香水產業的降龍涎香醚,以及測定Dysongensins A至H抗人類癌症細胞株的細胞毒殺作用與其抗病毒及抗發炎活性。因此,本發明由Dysongensin A製備降龍涎香醚提供了做為香水產業的香料的新管道,且新穎的二萜類化合物可用於製備抗病毒、抗發炎或抗癌的藥物組合物及/或藥物。
